I was finally approved for my life insurance policy. I mailed the premium in, and am 100% certain I’ll be hit by a bus in the day or two before they receive it, leaving my family penniless.
Need to have The Talk with my son soon. We bought a book to help, but unless that book can give the speech totally by itself without stammering, blushing, or inappropriate giggling, it’s of little help.
I’m rapidly scrolling past all social media posts celebrating autumn. Not sorry; not even a little. Fall is to winter as being shot in the brain is to death. For my part, I am striving not to complain about the dark seasons this year. It’s like being the only liberal in the financial district. There’s no point. No one cares.
If the construction remains on schedule and we bribe the right people at the Department of Buildings, I only have four more weeks of listening to Racist Greg every day. His latest trick is to berate his coworkers every morning on the phone with a mouth full of food. I’d shank him, except I expect one of those coworkers will do it first, saving me from prison.
Please, someone, make my calendars read-only for the next six months to prevent me from scheduling any more things because I clearly don’t know how to stop myself.
The people at ello are all about “WE ARE SO DESIGNERISH” but it’s ugly as fuck, you know? Yuck. I’m @scholvin there if you want to be budz but I don’t reckon to be there a lot.
The blossoming trend of blogging via twitter, and then screencapping those tweets to the tune of perhaps ten thousand vertical pixels, and then tumblring the resulting image sets my nerd teeth on edge. It’s like using the back tines of a claw hammer to turn a screw. Feasible does not imply optimal.
I’m far more interested in the Ryder Cup (even without Tiger) than I am in Bears/Packers this weekend. Keep up the good work, NFL.
Seems like our school district does a good job with normal kids, or kids with serious challenges. Kids with small- to medium-sized challenges? Not so much.
“FBI Director James B. Comey sharply criticized Apple and Google on Thursday for developing forms of smartphone encrytption so secure that law enforcement officials cannot easily gain access to information stored on the devices — even when when they have valid search warrants.”—
Meanwhile out here in flyover country, far from the scrutiny of the shamefully biased and disinterested east coast media, a quiet leader who no one anywhere would describe as “overrated” leaves the game this week, too.
2340 H, 439 HR (42nd all time), .841 OPS.
2005 ALCS MVP, and he hit the home run that turned that WS around.
Verbow was our labelmate for a little while in the late 90’s. That and $1.50 would get you a ride on the El. While we moved into ever seedier bars, they moved up to a deal with Epic and got Bob Mould to produce their excellent major label debut, Chronicles. You know how I feel about Bob. To describe me as “jealous” would be to describe last winter as “nippy.”
Bob’s influence is deep and obvious on this record, in a good way. He must have really liked working with them, too, since Jason Narducy is now touring with him on bass and/or rhythm guitar, depending on the configuration. Last couple times I saw them, they even did this song.
You never know what people are carrying around. You don’t know everyone’s burdens. People you think have it together aren’t always as together as you imagine. Everyone has their problems. You just never know what is going on in a person’s life unless they are willingly sharing it with you. So as you go through your day, just remember that nearly everyone carries some kind of burden. Treat people gently. Be kind to each other. Mean it when you ask “how are you?” and listen with your heart when they tell you. You may have your own cross to bear, but sometimes it’s necessary to put your own cross down and take up someone else’s. Make it lighter for them. Walk with them. Hold their hand. You never know what someone is going through.
So, so true. Especially, I think, in social media venues where it’s quite easy to portray one’s life in unrealistically positive ways. There’s so much unseen suffering all around us. In recent years, I’ve been trying harder to do what she suggests—to be kinder, to empathize more, or in some cases, just to not be a flaming jerk. I think I’m doing better, but that’s really for others to say.
As I thought about all this today, though, an unfortunately corollary appeared in my mind. Sometimes, we are the least kind to those whose struggles we know the most about. We are often at our most unkind with those we love. That needs to change, too. Those closest deserve that better treatment as much as anyone, maybe more. Something to work on.
(I’m saying “we” but I really mean “I.” But maybe it applies to you, too.)
Do any of you have any experience setting up a large iTunes library on a NAS to be shared across multiple computers/accounts around the house?
Can I holla some questions at you? My googling on the topic makes me think it’s a nightmare, but my current implementation (trying to sync N library instances via 3rd party apps) isn’t working, either.
Tuesday, Saturday, whatever. Days of the week are arbitrary and were (probably) established by a civilization that has been gone for millennia. Everything you see here is true, anyway.
I got some terrible news from a friend this week and my heart weighs a hundred pounds. Fuck cancer.
I started making a mental list of stuff I want to accomplish before turning 50 (2.388 years from now—mark your calendar) but I’m afraid to write it down since that feels like tempting the Universe in a dangerous way. But the Universe surely hears me thinking about it, so what’s the difference between that and writing it out?
It was boys night out here since the girls are at a baby shower. Danny and I went to a family friendly (really) local sports bar and were having a lovely time eating sammiches and watching football when a bunch of rabid, stinking drunks showed up straight from the Cubs game. “Daddy, why are they acting like that?” I realized he’d never seen drunken assholes before. I explained it. We got our check and left. I feel kinda bad, even though he took it in stride.
Both of my kids are young for their ages. Some might call them sheltered, or naive, or worse. I couldn’t care less. I hear the stuff their friends say and do, and I shudder. Too soon, man.
I got some other news this week that I’m still processing. A thing I thought was settled for the long haul may not be. So I’m struggling with my place in the fourth dimension right now, possibly obviously. Sorry for the vagueblog, but, hello—punch my stupid, insanely rare, hillbilly German name into google and this is the first place you land.
Researchers at the University of California, San Diego School of Medicine have launched a phase 1 human clinical trial to assess the safety and efficacy of a new monoclonal antibody for patients with chronic lymphocytic leukemia (CLL), the most common form of blood cancer in adults.
The new antibody targets ROR1, a protein used by embryonic cells during early development and exploited by cancer cells to promote tumor growth and metastasis, the latter responsible for 90 percent of all cancer-related deaths.
Because ROR1 is not expressed by normal adult cells, scientists believe it is a biomarker of cancer cells in general and cancer stem cells in particular. Because it appears to drive tumor growth and disease spread, they believe it also presents an excellent target for anti-cancer therapy.
Developed at UC San Diego Moores Cancer Center by Thomas Kipps, MD, PhD, who holds the Evelyn and Edwin Tasch Chair in Cancer Research, and colleagues, the antibody is called cirmtuzumab (also known as UC-961). In previous animal studies, Kipps’ team reported that ROR1 is singularly expressed on CLL and also on a variety of different cancers, including cancers of the breast, pancreas, colon, lung and ovary. In mouse models of CLL, ROR1 acts as an accelerant when combined with another oncogene to produce a faster-growing, more aggressive cancer.
Cirmtuzumab was developed under the auspices of the California Institute for Regenerative Medicine’s HALT leukemia grant awarded to Dennis Carson, MD, principal investigator, and Catriona Jamieson, MD, PhD, co-principal investigator to develop six distinct therapies against cancer stem cells. Kipps led one of the six projects and generated antibodies against ROR1, leading to the cirmtuzumab trial in patients with CLL.
“The primary goal of this phase I clinical trial is to evaluate whether cirmtuzumab is a safe and well-tolerated cancer stem cell-targeted agent in patients with CLL,” said Jamieson, chief of the Division of Regenerative Medicine, associate professor of medicine, director of stem cell research at UC San Diego Moores Cancer Center, deputy director of the Sanford Stem Cell Clinical Center and a principal investigator of the cirmtuzumab clinical trial.
Michael Choi, MD, assistant clinical professor of medicine and co-principal investigator of the clinical trial said, “The trial will involve patients with relapsed or refractory CLL, who will receive an intravenous infusion every 14 days at Moores, followed by regular monitoring and clinic visits to assess efficacy and identify and manage any adverse effects. Initial treatment is planned for two months.”
To learn more about eligibility for this clinical trial, call Reilly L. Kidwell at 858-534-4801 or Samuel Zhang at 858-534-8127.
We say “fuck cancer” here a lot. This might actually do it.
I’m a big, big fan of Apple products, but I’ll be skipping the watch. In fact, I’d been thinking about treating myself to a new analog watch this fall/winter (hi, Robin) and seeing the Apple watch makes me want a real one even more for some reason.
The next week is impossibly overscheduled, even by my ludicrous standards. Some good (recording studio!), some less so (the Jerz). The main bummer is that I won’t be around for the kids’ bedtimes 6 of the next 8 nights. This sucks for everyone involved.
I’m running in my first-ever organized 5K next Sunday. See previous point re: the state of my training. Ruh-roh, Raggy.
When I see that Tumblr Savior has blocked a recommended post and it’s also by a user I’ve likewise blocked, I stand right up and high-five myself. (If you are reading this, you are not blocked.) ((You guys would probably be pretty surprised by who is.)) (((Nope, never gonna tell.)))
Will one of you please drive me home? I’d prefer to have a big glass of bourbon and maybe a nap in the back seat. Msg me for deets. Thx.
1. Go to http://www.fcc.gov/comments 2. Click on 14-28 3. Comment “I want internet service providers classified as common carriers.” 4. Done
As we go through round N of the net neutrality fight, the phrase that pays is “common carriers.” That’s the same status that the phone companies had. It forces them to be completely agnostic about the content they carry, and just shut up and carry it.
Do this, and use that phrase when you talk to your whoevers in DC.
I can’t decide if it’s a feature or a bug that observing the socially correct minimum horizontal following distance on an escalator puts your face at someone’s exact butt level.
Something fierce, huge, and venomous has bitten my shin at a point where every nerve ending in my body apparently meets, a spot where there is coincidentally no muscle and not a lot of skin atop the bone, and I cannot express to you how much I want to blowtorch my own limb right now, jeebus, make it STOP.
Speaking of setting myself on fire, I’m car shopping right now. Worst first world problem? Worst first world problem.
After waiting far too long, I was finally stirred to action early this morning on a difficult-but-right thing to do, and then promptly thwarted by bureaucrats. I’m not done, though. (STM, kinda.)
What’s missing in a person’s life that leads them to be a self-described fan boi/grrl of a company that makes consumer electronics? And then drives that person to spend the day on twitter hammering the products and fan boiz/grrlz of competing consumer electronics companies?
I’m traveling to the Jerz for two days next week. Never been except for driving across, to and from NYC. I’m planning to dress, style my hair, and speak exactly like Paulie Walnuts to fit in better.
Belly fat, pattern baldness, lumbar discs, overactive maxillofacial nerves, early knee and shoulder obsolescence due to design flaws, tissue that inflames for no apparent reason. Engineering failures across the board. If I’d bought this contraption, I’d want a refund.
On that same thread: as has happened so many times before, just as I was making serious momentum on a fitness regimen, this wretched body decided to repay me with a massive bronchial infection that leaves me winded going up the stairs. After this likely 2-week+ setback I’ll get to start all over again. If I choose to bother.
I have listened to that a cappella thing I reblogged this morning a dozen times. It’s silly, maybe, but that kind of human achievement (the writing, the arrangement, the performances!) gets very close to what I consider spiritual. “Why we’re here”-level stuff. What we can do when all the lower tiers of the Maslow are fulfilled. And that leads to thoughts on why it’s so fucking important that everyone’s basic needs are taken care of. (Longer post on that, someday.)
I have overscheduled my September. Bad choice. As if it wasn’t bad enough that we are losing like 40 minutes of light every day, I went and did this to myself. Not helping.
The lighting tech (an A/V Club dropout, resplendent in a too-small black tee that said SECURITY and a scraggly beard that reached to his nipples) for a popular Quad Cities cover band called Cheeze Pizza (most notable for their fifty-something lead singer dressing in drag) tried to upstage us, then committed a heinous etiquette breach by starting to set up his shit 10 seconds after we finished, rendering me one more shoulder bump from committing a gruesome onstage homicide-by-lighting-truss-rectal-insertion.
Two friends—one dear, the other more of a FOAF—who I used to think were sensitive and intelligent have lived in close company with small-minded idiots for too long, and the effects are heartbreaking to see. Choose your companions wisely.
The backlash against the date-rape-drug-detecting nail polish baffles me. OF COURSE the priority is educating men and raising boys to end rape culture. Obviously. In this house we are working hard to raise our son exactly that way. HOWEVER, until the rest of the world catches up, and that may take a while, I want my daughter to have every possible tool at her disposal to protect herself. If this sort of thing saves even one woman, how is it bad? We can play offense and defense at the same time, and we should.
One Direction is pläying at Soldier Field tonight and there is a 60% chance of thunderstorms. Team Cloud!
I heard that the dev team at my previous employer was instructed six weeks ago to stop writing software. Due to the company being sold, TPTB didn’t want to risk any release-related production outages. So those engineers have been working short hours, surfing the web, looking for new jobs, etc. Fuck yeah, capital markets!
Bad At Marketing, Part CLXXVI: I’ll be playing with The Recliners again at Poopy’s in Savanna, IL this Sunday from 1-5. It’s the last big outdoor show of the season….come on out, maybe see one of your favorite farmers from northwest Illinois.